People

I am trying to establish novel therapeutic avenues to cure a broad spectrum of rare diseases.

Each rare disease patient potentially benefitting from the therapeutic approach I propose carries a missense mutation in a glycoprotein gene. The mutation impairs fold of the mutate glycoprotein but does not abrogate its function (responsive mutation).

My idea is that modulators of Endoplasmic Reticulum glycoprotein folding Quality Control (ERQC) and/or of Endoplasmic Reticulum Associated Degradation ...

In 2003 he formed the NBL with a Principal Investigator grant from SFI and funding from the Centre for Bioanalytical Sciences (an industry -academic collaboration). The research group focusses on the use of photonics and chemometrics technologies for life and physical science applications. In the Analytical Sciences, the primary emphasis is developing rapid, quantitative analytical methods for the analysis of complex materials with particular focus on biopharmaceutical manufacturing and he has ...