Investigations
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Submitter: Konstantinos Pyrgakis
Studies: Life-Cycle Analysis, Techno-Economic Analysis
Assays: No Assays
Submitter: Konstantinos Pyrgakis
Studies: Bioprocess Integration, Bioprocess synthesis
Assays: Downstream processing, Energy integration, Material and water integration, Upstream operations
Submitter: Konstantinos Pyrgakis
Studies: Bioprocess modeling
Assays: Conceptual and unit and process representation, Data collection on mass and energy balances, chemical and physical equil..., Modeling of unit processes (reactions, separations recycles), Process flowsheeting (process integration and recycles), Superstructure modeling and optimization
Submitter: Konstantinos Pyrgakis
Studies: Calculation of process variables
Assays: Calculate process variables
Submitter: Konstantinos Pyrgakis
Studies: Calculation of process variables
Assays: Calculate process variables
In the biopharmaceutical industry, nanobodies show promising properties for its application in serotherapy for serums targeting the most toxic components of scorpion venom. Nevertheless, the limited number of scientific publications on the production of nanobodies for antivenom productions poses a challenge. The reported yield is low (< 4 mg/L), biomass production is not reported, and the production in high cell density cultures have not been studied. Production conditions (temperature of ...
Submitter: Susana Alonso Villela
Studies: Characterization of E. coli WK6 strain under aerobic conditions, Characterization of E. coli WK6 strain under induction conditions, Recombinant nanobody CH10-12 and NbF12-10 production at low induction te..., Recombinant nanobody CH10-12 production at different induction temperatu...
Assays: Fed-batch culture of CH10-12 strain, induction at 28°C - BR02, Fed-batch culture of CH10-12 strain, induction at 29°C - BR06, Fed-batch culture of CH10-12 strain, induction at 30°C - BR03, Fed-batch culture of CH10-12 strain, induction at 32°C - BR07, Fed-batch culture of CH10-12 strain, induction at 33°C - BR04, Fed-batch culture of CH10-12 strain, induction at 37°C - BR05, Fed-batch culture of NbF12-10 strain, induction at 29°C - BR08, Fed-batch culture of WK6 strain, induction at 29°C - BR09, Fed-batch culture of WK6 strain, without induction - BR01
Submitter: Munazah Andrabi
Studies: Culture experiments, In-Silico Prediction, Metabolic model analysis, Validation of the secretome of Aspergillus niger
Assays: GPI Anchor Predictions, Growth experiment, Identify enzymes from spectra, Liquid chromatography tandem mass spectrometry, Mass Spectrometry Analysis, Obtain metabolic model, Obtain proteomes, Orthology identification, Signal Peptide Predictions
