Web page: https://www.wur.nl
Projects: Uncurated Protocols Library, Development Project, Muconic Acid Production, An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data, spreadsheet test, Example project, Template library
Institutions: WUR - Wageningen University & Researchhttps://orcid.org/0000-0001-8172-8981
Institutions: WUR - Wageningen University & Researchhttps://orcid.org/0000-0002-2352-9017
Head Chair of Systems & Synthetic Biology
The ecological niche occupied by a fungal species, its pathogenicity and its usefulness as a microbial cell factory to a large degree depends on its secretome. Protein secretion usually requires the presence of a N- terminal signal peptide (SP) and by scanning for this feature using available highly accurate SP-prediction tools, the fraction of potentially secreted proteins can be directly predicted.
However, prediction of a SP does not guarantee that the protein is actually secreted and current