Web page: https://www.wur.nl
Projects: IBISBA Library, Development Project, Muconic Acid Production, An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data, spreadsheet test, Example project, Template library
Institutions: WUR - Wageningen University & Researchhttps://orcid.org/0000-0001-8172-8981
Institutions: WUR - Wageningen University & Researchhttps://orcid.org/0000-0002-2352-9017
Head Chair of Systems & Synthetic Biology
The ecological niche occupied by a fungal species, its pathogenicity and its usefulness as a microbial cell factory to a large degree depends on its secretome. Protein secretion usually requires the presence of a N- terminal signal peptide (SP) and by scanning for this feature using available highly accurate SP-prediction tools, the fraction of potentially secreted proteins can be directly predicted.
However, prediction of a SP does not guarantee that the protein is actually secreted and current